SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef81b7c4a33d664f28aa487140245e441139b562d969ced1595d47bd2e566ec' 
  AND token = '4zit/hVJH4w0IaGkvzCh4NSjiGZJMNAriCMub5yDZ0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}