SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900e44449a244462015f3e125bec22ba303ffe025db8ede7d5d37a277b13a628' 
  AND token = 'h/529dkujJzRz9ib9i4OES4XCak3aq6WouTbGv35Bfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}