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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154ab0aefede105dfde42312df380cb9b28c5c06bf1d8825edcadf5d8be51c54' 
  AND token = 'oNbJmll/xdngzvDv7qbM2hQb3l16wRAtG9DdTTv0m60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}