SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5129130b36e935b131efe775b0ff5bfb21e5cb96448b7e9f8bd444e75099d309' 
  AND token = '9yBWnKOHhEqHjoHiEucqHmKa/BqvHi++xQTrzGv1UKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}