SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4def6909ea7a73b4bed9f2391e24f44b0eaba2d003516ded8d95582d6c3a26e4' 
  AND token = 'kgstUDFFrEO6q73JqlCIgRjQRmrwztb8kJ61Gw4U1nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}