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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0105e5daaef7a93e91045ea7fe7b5b9fcb6a6452acf104576c7e35d5cc6313d' 
  AND token = 'jUxDTXv/N/VP+0rbXG7/k+d98PQSGX4DZMPXJyAtH2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}