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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9319d5119cd5adc4368fad3b5a0cc8514fc8c70bf28de2087410eaff27cdb2' 
  AND token = '2kgQz1KXEv11AAYUPlVqxIBWAUSU6fXKaoxRdilD+jU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}