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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b11268884415c66290f562c41271070e05bc0231d5e0f9e65cc7b0f3a508090' 
  AND token = 'NfcJYo4m4ECPY+yYiFaZ4rsgdz5ESv9M4lLIR9EYMh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}