SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f8d0fe6001a8c6002dd1926dbb5d9efdb74532c4a25d3ba4eb59a044d6d409' 
  AND token = 'rmEORfDuq5OkionOGZW59l5qKJ4YPRBR2O43IUZcDgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}