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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b3684933ad358bec731490636283026f65904266339d45f7c392db63fb900d' 
  AND token = '2uDaF21j+M6hTIAp8idw8ZjyGbTg0RyvDgTF4UJ5MGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}