SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb602531df5d68e68c84848d2c0bb926e4f4b208bf585df1e2ed04b94575eff' 
  AND token = 'eqIgq68Yz7fiNF10KE0aaKdsAa2WF48+sbo8SMxLWk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}