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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed911a6d3d3ccc112022d22f41cdf8b331e470f7cdb24b7116f4b4520c24ba8' 
  AND token = 'GXXEtgNJ5WpWV0Hrlfe32RWk68Y0MOrMXX9sbBqa3Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}