SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785f3cb04570ab2da2effa66593c11962e6a960d5f8589b30f8b80bf93dd18f4' 
  AND token = 'Yf8nP4kwQs0NAquF/vk/1qRbmXKE7GY2AQQZrry6Ar0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}