SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '473a73a8b5e7a53b46f46938a6c57019bcea73e8b0b1bf8481086256a32ff9b5' 
  AND token = 'WuVbugXJ6y6RE45XtqX9sJmItBK1ofgPbSfx6y2StTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}