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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e28f8f46b7ef553c923dd48cc1f69c11de1d39e99194a9947f02bbf8b5e1022' 
  AND token = 'vBnx6inSC5S57AB2Cc3kpN+QfF+7L40JlfYOHz9PWc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}