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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386e8d7fb41de4d01022b2c7da1ccc56bcf778e047e4d8476285d9e477cba279' 
  AND token = 'UoR9QsrgKjCe/lzernyuu7814uz3HmJyyMUs1M4X7AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}