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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ea84456b2b631768a204a873acf03cafb4b95d196479667b1f07171bc68214' 
  AND token = 's3SmSnuHWiUKaRaPKTKqnAJZYbbVMn2+2HvS1xDJ2/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}