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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3d456d22bc85fd6bdc19e59a25124ea4a55d43d690201227e60e7d78973d78' 
  AND token = 'g8AC3DFd3EapU9OCFR1J1G7bkdQXObEXeDe8tNweDoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}