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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d0acc35aefbf18cda4988937b19180fd3c86f0054bec1d27c451002632f0f7' 
  AND token = 'jG+rDKm6Xak2TEgTEXTZ8N7cFxhRb2P+Doqe4jwu1Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}