SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7dfcbdf302dc380d3c12cc729a8848f1c1e1f72a9379431930d3746b7fd981b' 
  AND token = 'DjRB3QPCHD1B8yBV3A5CJ2DkccVLvH+qEKojNtGdUkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}