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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59554d312a2506965362f6a56fcb7cf4cb0d7330694cf01179913482d73360fd' 
  AND token = '8mqOJJTBe8lWH6GSKA0rGm/sogNrfE8gQ0IKq2OUfoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}