SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c41b3a8219f65f68a1f94f2d2052425877f359d8d11b7e2b15ca75ae99994e6' 
  AND token = 'uwZq+QfzIVDflnXMSStyTeVjDzAhAxJOBhTJy0yCqAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}