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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f42558f31c9479d60f707feea6a171ceca204724180bfc2ceaa8b66bb9b4e9c' 
  AND token = 'GUdtUq/SIXHyHBNLtB8Eqc1ZC2/bk1dYQSZg1D0V/r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}