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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86f46a0665c77f56b340cb70f550003405563e57a9f26818df19ad2390edcf4' 
  AND token = 'fka+NUFRZIjkyzVxHEpz7lrIjUpRUDZYnESlRD8qa8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}