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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e12fb76e1f915dd762297d80605d55ac9cbe777b53208dd9152a815714c228' 
  AND token = 'E6m36Ozq7vRf81hZfQoiTb9IBeh4oHj8faa6bNtGY1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}