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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c16fb90d14765c538d00092e3560c06079421859c40c89a8fdfe2c3453f9bcd' 
  AND token = 'r864An3U4Zsij+af8uSSshnjbc54vO9gJhxBI+enxaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}