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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b75986f45ce60b518a8061ecdeac2697d189cdf1166ada7b7dddaa276f6cced5' 
  AND token = 'zcROyCqNp8uBOdXzYOTNy6PC3lWOWiW1OoRZ75x2eLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}