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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563769e961c89ad123897f7af37f8b59a7b75b97cf51c5fe2b2b7a1e3b2528e5' 
  AND token = 'ZafnqOyysdy2AzKxJSCrDbTendTriWgxRCiRVG9wakY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}