SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0c70c6645d32fece91d1553084d187b62b7091bb04e494fdd2f1d84a55e13de' 
  AND token = 'foJYp3b2iFkmix/aNhvFQbLN5xlbb86WjTvPijkTMVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}