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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8e3198ccc4a7b3e36696e3dd69400dba2fd2669c551dcc8d86a32ef482b0a8' 
  AND token = 'JmVhGmSbqhDDbeD1g4dtnyJzRVCsdKE6WI3b0S0HlJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}