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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7276a7cd43240af9cec18279b2cd532febb6aedc6b798db4c0342ee7b02f3962' 
  AND token = 'ZgGAz/INpH6HFtN+RIY4SZe+8lK+GdxEHSuLW03zhZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}