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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e9fee957a2d1f884e653a3b733f061d979a65d574ea368322dc9b0a9108ec7' 
  AND token = 'EeymTFVmSkxfxUsFz+h2kS0zs8E4WOLrmoStcohUNw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}