SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae49c7d476f9fccc291050f2308cdc73774bd9fadbdcaae0bc930a38c1e45545' 
  AND token = 'ggzR/R4VnmwaSZdDJaCScd0lNdKXvSLeL/ikArQSZ+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}