SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f67e35d8aa62bceed9999391f18e73e6ee3d66ffff15de8f4146aeafaa7a35' 
  AND token = 'wx4FJzWtJ3W8qMd0OavQQa5yGq5jzbmN3g0f2Cim9oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}