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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d557be2f1d1975602039f082287669bef297d4eb5c7828d87dfed71120a78a' 
  AND token = 'VNMHgsz3Z0DmQa4D5cBvgyTwGvT2EJhwQp2c8kaT1Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}