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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c9125c7780c61267e4f062f89d4b4293feaf47688563c05d5acf853ecb22a2f' 
  AND token = '9POSaXRgrquxvUPFJD78UdFb4WolP45i4M6CkVe9B2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}