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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce9016066325d0e3a9f9ed3f497a92623a792827672e4e49b0a63b3a04e2f6fb' 
  AND token = '1DCXFwsIpkPyIsC4Ibm+37ENx1kwrr9dAwEY2L1pDAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}