SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0eaf5dd810107f83a9ea714da4b6cfc2122d29a91771a4ae9236ecaeb44710' 
  AND token = 'EAq+QPk6poG6tquLzd/eP4UJWfgeN6btlCllOjQ9k6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}