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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38218d2c1ec162257838a4ea2c03c910cab56d1c3b5e30c74c4e071704bd19f1' 
  AND token = 'gyTTuC4sHvBwG+uYsrxrRuAgKoa2P85l9dCdmDQP4eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}