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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb21c43b0239fb94e1b6046a7a43c6fccf71b6465c23ae1fc592b9783d5a82c6' 
  AND token = 'vtqkmliyLMjw4RTzKFdGjNcrEVn2XSoG0Cd9VDcIATU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}