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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de2bfef64121ccec3b6acd29814b89116aa6f76d766714dad4428480b76ac68' 
  AND token = 'jS4XQF2PFDavE7oWx+OdbBocN/FTECuac7kqAZ/skNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}