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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c4fc44f73aa27671ac27ee815d63924744d3bf5f94e8fa80bb05f411b13a13' 
  AND token = 'FYcIOni95Nf7u1mFsUQLHGsNpsYf9TzQITOexYvs908=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}