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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f10663898bdd7380a6ee346e73e033da560a235cde401f9a91ebbf9c867a46' 
  AND token = 'ew1P3yvBC5ZUEz6ABxAveN+pW3KT67DYrEKN3vxRPbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}