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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a3be3376a04720989ad3887c3598a42a4b02498d33cdf60b99625d2cca2469' 
  AND token = 'cBvFE/C3Eo1ozk4AJIbBAg595ZSYBn8eZc9WAGWJCj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}