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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f28f2b1bd522217dca0986a09ce3bee7d1fe9cad4f4f99ebdba79ad77c7f2c' 
  AND token = 'b8T54N3QCHjddaYFwsKCEmv6xfzn7GeQe/m1G/wF17o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}