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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd002fe15b73829ae3b618a35adc21ce77c534a2c9bdb5d405737a7cffb459078' 
  AND token = 'ZKd/65DwXOe2sn9oCGb2xZCzFj03BU5Ukc2vkZuR/oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}