SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1948f0bc01b663442bf6d9700881f66525d150496bc120eb0cde2bcc72b41b' 
  AND token = 'hRt6yKjiOgvIe1gkiZDmqy50kOt08Mrb4Drha/u6NJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}