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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33adf842706001a7cdd67177cc89e186e85b34ea1e65e004edadcf65c59306ad' 
  AND token = 'CW/m7wdQgSaqnIgNYMiX+aK7wAdNbyiSPN4OoZ38ttw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}