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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5064e2504f62c69d71c2af460e1ddd61b255da1a8b38cb57121cf374acbdcef2' 
  AND token = 'kk+d+S4icVP3Mzn9sVpm9xOk1CEjVMU+/QhrSjEDZ2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}