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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab2f76de926ed21bcf7b6f14521f5d6ed4f85e5cf1cc51f2ed8ea437b171a0f6' 
  AND token = 'sNSwXERIaNG01c34jYnlr6GvyYY7YjhWFD/60A3dG0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}